Biocompatible Film‐Coating of Magnetic Soft Robots for Mucoadhesive Locomotion

Magnetically-actuated soft robots for medical applications are required to be functional, biocompatible, as well capable of robust motion inside human organs. In this paper, a ring-shaped magnetic robot, with flexible biopolymeric film coating, on mucus-coated surfaces is designed and investigated. The made from chitosan–glycerol (C–G) solution endows the robot locomotion capabilities diverse geometrical shapes orientations. By utilizing mucoadhesive locomotion, has potential carry out clinical procedures enclosed tissue surfaces. Material characterization shows that mucoadhesion increases increase contact times and/or preload forces. softness C–G can adjusted by controlling concentration glycerol. design magnetization profile decouple functions robot. Additionally, film-coated tested biocompatible colorectal adenocarcinoma cell line epithelial morphology (HT29). reduces negative effects (superoxide generation) ferromagnetic particles. Three including pick-and-place, cargo transportation, liquid capsule release demonstrated different show maneuverability, functionality, implementing through mucoadhesion.